DOI
(Dimethoxyiodoamphetamine)
TrippyWiki score: 7.6/10
TABLE OF CONTENTS
What is DOI?
DOI (Dimethoxyiodoamphetamine) is a psychedelic substance of the amphetamine class that was first synthesized by Alexander Shulgin in 1972. The effects are similar to those of LSD, the main difference is that DOI lasts for much longer and it has stimulant qualities. The drug is almost identical to DOM, DOB, and DOC.
Why choose DOI over other psychedelics?
DOI…
Long-term benefits & side effects
Many of the benefits will only occur if you follow the tips below.
Most (if not all) of the side effects are preventable and they will not happen if you follow the Safety checklist.
DOI…
How to take DOI
Administration
DOI is mostly sold on a blotter or as a pill but you can also buy it in gummy bears or in a liquid form. Either way, you can either swallow the substance or let it dissolve on your tongue.
Always test your blotter with a Marquis Reagent Testing Kit because 25I-NBOMe is sometimes sold as DOI and it can be extremely dangerous even in a tiny amount. If the drug turns brown, you have NBOMe.
If you are not willing to do this, swallow the substance. If you do so, NBOMe should not affect you in any way.
If you stick the tab under your tongue, the drug will dissolve a little faster and it will take slightly less time to notice the effects.
Dosage
It’s been shown that mystical experiences can deeply change your identity and the higher the dose you take, the more intense they will be.
Do not, however, start with a strong dose if you don’t have a trip sitter nearby.
A strong dose can easily cause you to reach a breakthrough where you lose sense of the physical world. You will become so conscious that you will “go unconscious.”
The last thing you want is to be lying on the ground for hours in nature, let alone on a street or in a club.
So keep in mind that the higher the dose you take, the more important it is to be in a safe environment.
Some people are more sensitive than others. There are people who can take a relative or even a strong dose and feel nothing. This mainly happens to people with autism. Otherwise, it is rare.
Equivalents for 1.5 mg of DOI
The effects of the psychedelics below are not the same as the effects of DOI. This chart only compares the intensity of each substance.
DOM | 4 mg |
DOB | 1.5 mg |
DOC | 3 mg |
DOI | 1.5 mg |
LSD | 100 µg |
Dry Mushrooms | 1.7 grams |
Mescaline | 250 mg |
Moringa Glory (LSA) | 150 seeds |
HWB (LSA) | 6 seeds |
1P-LSD | 100 µg |
ETH-LAD | 75 µg |
AL-LAD | 115 µg |
ALD-52 | 110 µg |
LSZ | 125 µg |
25I-NBOMe | 600 µg (can be dangerous!) |
4-AcO DMT | 15 mg |
4-HO MET | 16 mg |
Safety checklist
Maximize the benefits
Keep in mind that integration is even more important than the trip itself. Taking psychedelics would be almost useless if you didn’t retain any lessons in your day-to-day life.
What will help you the most is contemplating about the experience – be it by journaling, thinking about the trip, or sharing your memories with a trusted friend.
Distracting thoughts can get in the way, which is why you want to spend the day after your trip without TV, social media, and other distractions.
If you can, spend time in silence and solitude. Meditate, go for a walk, contemplate the experience.
Should you listen to music on DOI?
Music can make the trip more pleasant and greatly increase the benefits. That is why it is used in most psychotherapy sessions.
However, not all music is created equal. Listening to N.W.A. and 2Pac wouldn’t be so helpful. Even positive, relaxing music with lyrics can be a distraction.
If you decide to listen to music on psychedelics, choose calm, classical music with little to no lyrics.
This playlist used in Johns Hopkins psilocybin studies is proven to be extremely effective:
The author of the playlist, Roland Griffiths, went over hundreds of songs and only chose the best of the best based on how his patients responded to the music.
The music should be loud enough so you can hear it clearly but not unpleasantly loud. If you can, play it in your headphones.
Duration
Onset = 1-2 hours
Come up = 2-3 hours
Peak = 5-10 hours
Come down = 5-10 hours
What does DOI feel like?
The effects of DOI are virtually identical to a more famous DOM and comparable to those of LSD. The main difference between DOI and LSD is that DOI also acts as a stimulant and lasts for much longer (approximately 1.5x longer).
The drug also makes users more sociable. This effect is similar to what MDMA users experience.
Other common effects include:
Euphoria
Music enhancement
Increased creativity and open-mindedness
Mindfulness, being present
Higher capability for love and compassion
Pain relief
Feeling one with all that is
Seeing life from a different perspective
Appreciating small things
Higher energy
Increased awareness
Stamina enhancement
Feeling your emotions more intensely
Memory suppression
Time distortion
Inability to sleep
Visual effects (enhanced colors, seeing patterns in everything, distortions, …)
Getting stuck in a thought loop
Confusion
Nausea
Headache
Inability to focus
Increased body temperature
Increased heart rate
Worse thermoregulation
Difficulty urinating
Anxiety, paranoia
Vulnerability
The higher dose you take, the more intense these effects will be.
With that said, it is impossible to accurately describe the experience through human language.
The psychedelic affects each individual differently and no two trips are the same. Therefore, there is virtually no way to know what your trip will feel like.
The only way to truly know what DOI feels like is to try it.
The substance will most likely give you a pleasant experience. Bad trips can happen but you can prevent them by following the tips below.
Bad trips
Bad trips mostly happen because people take the substance irresponsibly. If you take this psychedelic the right way, there is virtually no chance you’ll get a bad trip.
In case you still do, that’s good! A “bad” trip isn’t always bad, it can actually be the most healing and insightful moment of your life!
During a “bad” trip, negative emotions are coming up from your subconscious mind. They have always been there whether you are aware of it or not. They have been damaging your life and a difficult trip is an opportunity to process these traumas and unpleasant feelings and let go of them.
The more painful the experience, the more you can heal.
So instead of calling bad trips bad, call them challenging.
If you understand that bad trips are awesome in the long run, not only will you feel more comfortable diving into these challenging states, it will actually excite you!
Why they happen
The most common reasons for getting a bad trip are:
How to cope with a bad trip
How to end a bad trip
In case you are not ready to face your inner demons yet, there are a few ways to end a bad trip.
One possible way is to put on music that is familiar to you. Another way is to switch up your location and move from one place to another. This can completely change your train of thought.
In case the trip becomes extremely challenging and there is no one around you to keep you safe, consider ending your trip with a trip killer.
Using a trip killer usually is not the best idea because the bad emotions will stay unresolved and you will get little to no benefits from the experience. With that said, using a trip killer is smarter than harming yourself.
The 2 best options that you have for ending a bad trip are Phenibut and benzodiazepines.
Phenibut is generally safer. The downside is that it can take hours to kick in.
So to end a trip, use benzodiazepines but only do this if you completely have to.
Interactions
Microdosing
Microdosing DOI might be even more beneficial than microdosing LSD. This is because the DOx family seems to have anti-inflammatory properties.
However, we don’t have enough data to know for certain that DOI is safe when taken on a regular basis for a long period of time.
If you are going to microdose DOI, do so every 3rd or 4th day. Taking a microdose more often is not a good idea because you would become tolerant to the substance and it would have little to no effect.
Around 80% of people who take LSD microdoses claim that it has profoundly changed their lives. This is likely the case for DOI as well.
For some, microdosing has cured their depression and helped them find beauty in small things. Some also say that they experience significantly less anxiety when they microdose.
Many people take tiny doses of acid to become more creative and productive throughout the day. Microdosing has also been shown to increase athletic performance.
What is awesome about microdosing is that you can stop at any time in case you notice some adverse reaction or if you simply don’t see any benefits.
How to microdose
Put your blotters into distilled water Keep the water in a cold dark place for 24 hours to make sure your tab has fully dissolved into the liquid.
Put the liquid into your fridge so that the substance doesn’t oxidize. If you store your substance in the fridge, it will last for up to a year there, sometimes even longer. The same applies to a freezer.
Take the liquid every 3rd day, preferably on the days you want to be the most creative.
Do so in the morning so that the substance doesn’t interfere with your sleep.
Legality
As of 2021, DOI is illegal in almost every country.
In many countries, you can legally own a small amount of the substance for personal use (in Mexico and Portugal, for example).
FAQ
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Thank you for taking psychedelics responsibly, immature psychonauts are the last thing the psychedelic movement needs.
And thank you for being a part of this renaissance. Together, we can change the world!