2C-E

(Aquarust, Eternity)


TrippyWiki score: 8.2/10

What is 2C-E?

2C-E is a psychedelic substance of the phenethylamine class. The drug shares many similarities with a more famous 2C-B and its effects are somewhere between LSD and MDMA.

Why choose 2C-E over other psychedelics?

2C-E…

  • Doesn’t cause a “bad trip” as often as most other psychedelics
  • Works as an aphrodisiac
  • Allows you to have cleaner thoughts than if you were to take LSD or magic mushrooms, for example
  • Is one of the best psychedelics for beginner psychonauts

Long-term benefits & side effects

Many of the benefits will only occur if you follow the tips below.
Most (if not all) of the side effects are preventable and they will not happen if you follow the Safety checklist.

2C-E…

  • Is an effective way to treat depression and PTSD
  • Helps people socialize and overcome their social anxiety
  • Is being used to cure addictions
  • Might help you form positive habits, such as meditation and exercise
  • Increases neuroplasticity
  • Makes you more creative and open-minded
  • Helps you look at your life from a different perspective
  • Allows you to heal your childhood trauma and forgive people who’ve hurt you
  • Makes you more conscious and loving
  • Can help you transcend the fear of death
  • Gives you insights into the nature of reality
  • Can be used for treating autism
  • Makes you appreciate nature more
  • Is an effective way to treat cluster headaches
  • Might not be real 2C-E and can instead be a physically dangerous substance (Bromo-DragonFLY is a common substitute)
  • Has led to self-harm by people who took it in an unsafe environment
  • Might speed up the onset of schizophrenia if you’re genetically predisposed to it
  • Can cause HPPD and physical damage if you combine it with other substances (such as alcohol or stimulants)
  • Could cause you trauma due to bad set and setting
  • Might lead to drug-induced psychosis if you’re predisposed to it
  • Can be psychologically addictive (but only if you use the psychedelic recreationally)
  • Can cause seizures in rare cases
  • Is illegal in many places and you might get arrested for getting involved with the substance
  • Could cause heart problems at high doses (especially when snorted)

How to take 2C-E

Administration

You can either buy 2C-E in a pill or a powder. If you can, choose powder. Not only is a powdered form more likely pure but the amount of 2C-E in a pill can also vary greatly. On average, the pill contains 20-40% less 2C-E than what the dealer tells you.

Either way, it is best to test your substance with a Marquis Reagent Testing Kit before you put it in your mouth.

Oral

This method is the easiest and the most common.

Snorting

Snorting 2C-E can be extremely painful.

The benefit of using this route of administration is that you’d need to take a much lower dose (approximately 2 times lower). The drug would also kick in faster and leave your system earlier.

Snorting high doses of 2C-E may not be safe, especially if you suffer from heart problems.

Vaporizing

Vaporizing the drug instead of eating it doesn’t seem to have any benefits. The experience will also not last for as long.

Plugging

Taking 2C-E rectally is a good option for many reasons:
1) You will only need around half of the amount of the drug then if you were to take it orally.
2) Plugging the substance won’t cause you as much nausea as if you swallow it.
3) With this method, it is safe to eat before you take the drug.
4) Plugging is a lot less painful than snorting.
5) The drug will kick in faster and your trip may last for longer.

How to plug 2C-E

Empty your bowels before you plug.

Mix every 10 mg of the drug with 0.1 ml of filtered water. Let the drug completely dissolve into the water.

Use a 1 ml syringe, put the liquid into it and plug the substance into your a#s.

You need to put the syringe deep enough but not too deep either. What will help you achieve this is putting a rubber band around the 0.6 ml. That way, you will know when to stop.

After you pour the liquid into your system, wait for 1-2 minutes, then pour the syringe out and go lay on your bed or the ground.

Dosage

Oral

  • 2 mg = Threshold
  • 5-10 mg = Light dose
  • 10-15 mg = Regular dose
  • 15-30 mg = Strong dose
  • 30+ mg = High dose

Snorted / Plugged

  • 1 mg = Threshold
  • 3-5 mg = Light dose
  • 5-8 mg = Regular dose
  • 8-15 mg = Strong dose
  • 15+ mg = High dose

It’s been shown that mystical experiences caused by 2C drugs are responsible for most of the therapeutic benefits and the higher the dose you take, the more intense they will be.

Do not, however, start with a strong dose if you don’t have a trip sitter nearby.

High doses can easily cause you to reach a breakthrough where you lose sense of the physical world. You will become so conscious that you will “go unconscious.”

The last thing you want is to be lying on the ground for hours in nature, let alone on a street or in a club.

So keep in mind that the higher the dose you take, the more important it is to be in a safe environment.

Some people are more sensitive than others. There are people who can take relatively high doses and feel nothing. This mainly happens to people with autism. Otherwise, it is rare.

Safety checklist

Maximize the benefits

Keep in mind that integration is even more important than the trip itself. Taking psychedelics would be almost useless if you didn’t retain any lessons in your day-to-day life.

What will help you the most is contemplating about the experience – be it by journaling, thinking about the trip, or sharing your memories with a trusted friend.

Distracting thoughts can get in the way, which is why you want to spend the day after your trip without TV, social media, and other distractions.

If you can, spend time in silence and solitude. Meditate, go for a walk, contemplate the experience.

Duration

Onset = 15-45 minutes
Come up =
1-2 hours
Peak =
3-5 hours
Come down =
2-3 hours

  • You should notice the first effects within 40 minutes after you take the psychedelic
  • You will reach the maximum effect around the 2-hour mark
  • The whole trip usually lasts for 6-10 hours
  • At heroic doses, your trip may last for even longer
  • If you take the substance orally and you eat food before your trip, the substance will take longer to kick in

What does 2C-E feel like?

2C-E is usually darker and less gentle than 2C-B. The drug often shows the user skulls, blood and other unpleasant visuals.

This, however, doesn’t have to be negative. The reason why we find these images scary is because of our conditioning.

2C-E also allow you to be more introspective and derive more benefits from the trip than 2C-B.

Like with 2C-B, psychonauts describe the 2C-E experience as something in-between LSD and MDMA. With that said, candy flipping (mixing LSD and MDMA) feels fairly different than taking any drug from the 2C-X class.

2C-E often acts as an incredibly potent aphrodisiac.

Another experience specific to the 2C-X family is body tripping (body high). The drug creates a unique tingling sensation that is often combined with your body feeling extremely tired. This effect will be euphoric if you surrender to it but it can also become uncomfortable if you try to resist it.

Other common short-term effects include:

Euphoria
Increased creativity and open-mindedness
Mindfulness, being present

Higher capability for love and compassion
Pain relief
Feeling one with all that is

Seeing life from a different perspective
Appreciating small things
Higher energy
Increased awareness
Stamina enhancement

Feeling your emotions more intensely
Memory suppression
Time distortion
Visual effects (similar to LSD but weaker)

Confusion
Nausea
Headache
Inability to focus
Increased body temperature
Increased heart rate
Worse thermoregulation
Difficulty urinating
Anxiety, paranoia

Vulnerability

The higher dose you take, the more intense these effects will be.

With that said, it is impossible to accurately describe the experience through human language.

The psychedelic also affects each individual differently and no two trips are the same. Therefore, there is virtually no way to know what your trip will feel like.

The only way to truly know what the drug feels like is to try it.

2C-E will most likely give you a pleasant experience. Bad trips can happen but you can prevent them by following the tips below.

Bad trips

Bad trips mostly happen because people take the substance irresponsibly. If you take this psychedelic the right way, there is virtually no chance you’ll get a bad trip.

In case you still do, that’s good! A “bad” trip isn’t bad, it can actually be the most healing and insightful moment of your life!

During a “bad” trip, negative emotions are coming up from your subconscious mind. They have always been there whether you are aware of it or not. They have been damaging your life and a difficult trip is an opportunity to process these traumas and unpleasant feelings and let go of them.

The more painful the experience, the more you can heal.

So instead of calling bad trips bad, call them challenging.

If you understand that bad trips are awesome in the long run, not only will you feel more comfortable diving into these challenging states, it will actually excite you!

Why they happen

The most common reasons for getting a bad trip are:

  • Tripping in an unsafe environment (in public, at a party, even nature doesn’t feel safe if you take higher doses)
  • Facing difficult times in your day-to-day life (a break-up, death of a loved one, …)
  • Rejecting to let go and trying to hold on to your ego and control the state
  • Being afraid of the trip (either because of the stigma around psychedelics or because you are not sure how pure your substance is)
  • Mixing the psychedelic with alcohol, weed, or other drugs
  • Expecting a bad trip (it can easily become a self-fulfilling prophecy)

How to cope with a bad trip

  • Do not perceive this experience as something bad, remember that facing these difficult emotions is extremely healing
  • Fully surrender to the experience, do not try to feel good
  • If you’re alone, call a trusted friend to come over and keep you safe

How to end a bad trip

In case you are not ready to face your inner demons yet, there are a few ways to end a bad trip.

One possible way is to put on music that is familiar to you. Another way is to switch up your location and move from one place to another. This can completely change your train of thought.

In case the trip becomes extremely challenging and there is no one around you to keep you safe, consider ending your trip with a trip killer.

Using a trip killer usually is not the best idea because the bad emotions will stay unresolved and you will get little to no benefits from the experience. With that said, using a trip killer is smarter than harming yourself.

The 2 best options that you have for ending a bad trip are Phenibut and benzodiazepines.

Phenibut is generally safer. The downside is that it can take hours to kick in.

So to end a trip, use benzodiazepines but only do this if you completely have to.

Interactions

  • Qualia Mind
    This nootropic is comprised of 28 ingredients designed to support and maximize your brain function. These ingredients act synergistically and many of them will protect you from the neurotoxic effects of psychedelics. Qualia will also make your trips more pleasant and help you retain more benefits from them.
  • Herbs
    Herbs can help calm you down. Herbal teas (chamomile, lemon balm, valerian root, …) are especially helpful.
  • Green tea
    Tea makes you both more alert and calm at the same time. It also contains neuroprotective antioxidants, such as EGCG.
  • CBD
    CBD has a calming effect.
  • Weed
    Marijuana will greatly intensify the trip.
  • MDMA (Nexus flipping)
    MDMA will ease the comedown and help you solidify the insights from the experience. Unfortunately, combining these substances is likely to cause neurotoxicity. On top of that, some users react negatively to this combination.
  • Nitrous oxide
    Nitrous oxide will multiply the intensity of your trip.
  • Dissociatives
    Combining dissociatives with psychedelics won’t necessarily cause you harm but it can be confusing and lead to bad trips.
  • Benzodiazepines (Valium, Xanax, …)
    Benzos will end your psychedelic experience within 40 minutes but using this method may cause you side effects in the long run.
  • Alcohol
    Alcohol minimizes all the potential benefits of a psychedelic experience. It also greatly increases your chance of having a bad trip.
  • SSRIs or MAOIs
    Not only will these antidepressants greatly decrease the intensity of your trip, but they can also lead to long-lasting side effects.
  • Lithium
    Combining psychedelics with lithium significantly increases the risk of seizures and psychosis.
  • Stimulants
    The combination can easily lead to heart problems, even if you’re a healthy individual.
  • Tramadol
    Combining the two can cause seizures.
  • St. John’s Wort
    This combination may lead to serotonin syndrome.

Legality

As of 2021, 2C-E is illegal in most countries of the world.

In many countries, you can legally own a small amount of the substance for personal use (in Portugal and the Czech Republic, for example).

FAQ

You have to wait for several days in-between your trip to refresh your tolerance.

If you were to trip 2 days in a row, your 2nd trip would be extremely weak.

How many days does it take to become sensitive to the drug again?

This mostly depends on the dose. At regular doses, it takes approximately 7 days to become sensitive again.

So you could technically take the drug every week but if you want to maximize the benefits, do not trip before you integrate all the lessons from your last trip.

Counter-intuitively, you might get more benefits by tripping less often.

That is why you may only want to trip once or twice a month or just a couple of times a year.

As your trips get more and more intense, you will not want to trip nearly as often anyway.

The drug either blocks or minimally activates the 5-HT2A receptors. It also affects your 5-HT2C receptors.

With that said, the only way to truly know what this psychedelic does to your brain is to try it yourself.

Most importantly, you need to trip in a safe place where there are no strangers around.

Tripping at home is safer and better for personal growth while taking psychedelics outside will help you develop a strong connection with nature.


Beware that the drug is likely going to cause body load and make your body extremely tired. You may not be able to move so never trip in an unsafe environment.

If you are a mentally stable individual who does not suffer from psychosis or have a predisposition to schizophrenia, there is virtually no way you would develop any mental illnesses because of taking the psychedelic.

The drug will stay in your oral fluid for 16-24 hours.

With that said, the substance is extremely hard to detect and standard drug tests are not capable of that.

Most users don’t enjoy the taste of the drug. It tastes extremely bitter and chemically.

Order a Marquis test kit and follow the instructions on its label. You can be sure your substance is from the 2C family if the test shows a green color.

Keep your powder or pills in a cold dark place, preferably with no air.

If you don’t do this, the drug will lose potency within a few weeks or months.

When you store the substance well, it will last for years or even decades.

You can microdose with 2C-E but drugs like LSD, psilocybin, and ibogaine are more suited for this.

If you take the substance orally, stop eating at least 2-3 hours prior. If you eat food before you take the drug, you will most likely experience extreme nausea and may even vomit. If you plug the drug, you do not have to worry about this.

  • Those who suffer from heart problems
  • Immature people who are not willing to follow the safety guidelines
  • People who suffer from psychosis
  • People who have a familial history of schizophrenia
  • Those who suffer from HPPD
  • People who are going through a manic phase of bipolar disorder
  • If you’re going through extremely challenging times, you can take psychedelics but the trips might be unpleasant, beware of that

Thank you for taking psychedelics responsibly, immature psychonauts are the last thing the psychedelic movement needs.

And thank you for being a part of this renaissance. Together, we can change the world!

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